某飞机失事后109名乘客仅数名幸存。心理医生克莱尔(安妮•海瑟薇Anne Hathaway 饰)被导师派去对幸存者进行心理治疗,却发现自己渐渐爱上幸存者之一,前证券公司副总裁艾瑞克(帕特里克•威尔森 Patrick Wilson 饰)。与此同时,克莱尔发现诊所外经常有人监视,自己被跟梢,病人神秘失踪,甚至航空公司职员也来威胁她不要多管闲事,这令克莱尔怀疑航空公司为掩盖机械故障的事实,故意用操作失误来掩人耳目避免调查,进而对察觉真相的幸存乘客施以毒手。随着克莱尔与艾瑞克感情的深入,病人竟变得越来越少,克莱尔与姐姐一家也失去联络,甚至就连她的自身安全也面临威胁……
A village in Ukraine, near the Russian border. The only thing that slightly disturbs the peace there is the occasional death of an elderly person. That is also why Anatoly returns there: to take care of his dying mother.